Table 4.
Genes up-regulated by DPTA-NONOate in Entamoeba histolytica HM-1:IMSS. The probe ID, accession number, description, baseline expression level, fold-change, p-value, and regulation under other conditions are shown. The 30 most highly regulated genes are listed. HS (heat shock) (adapted from Hackney et al); Colitis (ameba from a mouse model of amebic colitis) (adapted from Gilchrist et al); Cysts (E. histolytica cysts) (adapted from Ehrenkaufer et al).
| Probe ID | Accession number | Description | Baseline expression level | Fold-change | p-value | Regulated under other conditions? |
|---|---|---|---|---|---|---|
| 194.m00102_s_at | XM_645780 | hypothetical protein | 0.06 | 380.2 | 0.009 | HS |
| 363.m00049_x_at | XM_643869 | hypothetical protein | 0.17 | 305.5 | 0.002 | - |
| 256.m00084_x_at | XM_644865 | hypothetical protein | 0.12 | 252.8 | 0.002 | - |
| 248.m00060_s_at | XM_644979 | hypothetical protein | 0.05 | 240.9 | 0.006 | - |
| 692.m00024_s_at | XM_642872 | hypothetical protein | 0.05 | 219.5 | 0.003 | - |
| 194.m00123_x_at | XM_645776 | dUTP diphosphatase, putative | 0.11 | 191.5 | 0.003 | - |
| 266.m00066_s_at | XM_644755 | hypothetical protein | 0.13 | 176.2 | 0.004 | - |
| 654.m00032_x_at | XM_642891 | hypothetical protein | 1.39 | 162.9 | 0.015 | - |
| 654.m00031_s_at | XM_642894 | hypothetical protein | 0.06 | 130.4 | 0.008 | - |
| 256.m00083_x_at | XM_644864 | hypothetical protein | 1.22 | 123.6 | 0.006 | - |
| 397.m00055_s_at | XM_643659 | hypothetical protein | 0.18 | 119.3 | 0.004 | - |
| 692.m00026_s_at | XM_642873 | hypothetical protein | 0.06 | 107.7 | 0.010 | - |
| 375.m00057_x_at | XM_643790 | deoxyuridine 5 -triphosphate nucleotidohydrolase | 0.05 | 82.54 | 0.020 | - |
| 711.m00021_x_at | XM_642861 | hypothetical protein | 0.10 | 81.62 | 0.006 | - |
| 397.m00062_x_at | XM_643664 | hypothetical protein | 1.35 | 58.47 | 0.019 | - |
| 397.m00054_x_at | XM_643658 | hypothetical protein | 0.06 | 57.66 | 0.020 | - |
| 36.m00211_at | XM_650002 | hypothetical protein | 0.09 | 49.28 | 0.005 | - |
| 245.m00039_x_at | XM_645025 | hypothetical protein | 0.47 | 22.34 | 0.014 | - |
| 301.m00039_s_at | XM_644356 | heat shock protein 70, putative | 0.30 | 21.14 | 0.003 | - |
| 81.m00150_s_at | XM_648418 | heat shock protein 101, putative | 1.54 | 20.48 | 0.001 | - |
| 450.m00030_at | XM_643384 | hypothetical protein | 0.20 | 19.96 | 0.027 | Colitis |
| 356.m00029_s_at | XM_643911 | hypothetical protein | 0.18 | 16.2 | 0.008 | - |
| 7.m00453_s_at | XM_651737 | hypothetical protein | 0.30 | 14.84 | 0.001 | - |
| 344.m00044_at | XM_644000 | hypothetical protein | 0.24 | 13.53 | 0.033 | Cysts |
| 295.m00030_at | XM_644416 | conserved hypothetical protein | 0.16 | 13.28 | 0.048 | - |
| 134.m00124_at | XM_646949 | heat shock protein, Hsp20 family, putative | 1.44 | 12.29 | 0.016 | - |
| 33.m00209_x_at | XM_650174 | hypothetical protein | 0.10 | 12.1 | 0.004 | - |
| 141.m00082_at | XM_646820 | protein kinase, putative | 0.54 | 12.09 | 0.027 | - |
| 20.m00272_x_at | XM_650868 | conserved hypothetical protein | 0.17 | 9.86 | 0.043 | - |
| 796.m00013_s_at | XM_642828 | conserved hypothetical protein | 0.23 | 9.69 | 0.015 | - |