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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Acta Biomater. 2011 Nov 20;8(4):1401–1421. doi: 10.1016/j.actbio.2011.11.017

Fig. 2.

Fig. 2

Schematic of CaP NPs for drug delivery applications: single shell (a and b), multi-shell (c), and surface functionalization approach (d). Fluorophore agents can be entrapped/doped into CaP core as shown in (b) for imaging. The multi-shell approach (c) is more effective for nuclear transfection than the single shell as in (a). Drugs or biomolecules that are poorly adsorbed on CaP can also be adsorbed on the surface functionalized polymer coating as shown in (d).