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Correlation coefficient (R2), rate constants (K) and half time (t1/2) obtained by fitting the perindopril release data from PMAE nanocomposite into solutions at pH 4.8 and 7.4
| pH | Saturation release (%) |
R2
|
Pseudo-second order
|
|||
|---|---|---|---|---|---|---|
| Pseudo-first order | Parabolic diffusion model | Pseudo-second order | Rate constant, K (mg/min) × 10−5 | t1/2 (min) | ||
| 7.4 | 100 | 0.7739 | 0.7006 | 0.9901 | 3.17 | 315 |
| 4.8 | 100 | 0.9651 | 0.9190 | 0.9953 | 6.30 | 145 |
Abbreviation: PMAE, perindopril intercalated into Mg/Al by ion-exchange.
