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. 2012 Aug 1;7:4223–4237. doi: 10.2147/IJN.S34105

Figure 2.

Figure 2

In vitro degradation of IgG under GI-mimicking conditions. 125I-IgG was incubated for the indicated time periods in SGF with or without pepsin, or SIF with or without pancreatin, and the percentage of 125I-IgG degradation was calculated as described in Figure 1. Curves were fitted by software regression analysis.

Note: Data are mean ± SEM (n ≥ 3 per experiment and at least two independent experiments).

Abbreviations: SGF, simulated gastric fluid; SIF, simulated intestinal fluid; SEM, standard error of the mean.