Table 1.
Characterization of polymer NCs
| NC surface coating: | None | IgG | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| Dispersant: | PBS | SGF | SIF | PBS | SGF | SIF |
| Diameter (nm) | 157.1 ± 3.5 | 157.2 ± 1.4 | 150.4 ± 2.3 | 269.8 ± 6.3 | 312.7 ± 3.6 | 285.1 ± 6.9 |
| PDI | 0.169 ± 0.009 | 0.097 ± 0.008 | 0.125 ± 0.010 | 0.353 ± 0.013 | 0.171 ± 0.009 | 0.211 ± 0.013 |
| Zeta potential (mV) | −6.4 ± 0.5 | 21.6 ± 0.6 | −16.4 ± 0.8 | −7.1 ± 0.2 | 17.7 ± 1.0 | −10.0 ± 0.5 |
Notes: Data are mean ± SEM (n ≥ 3).
Abbreviations: NC, nanocarrier; PDI, polydisperity index; PBS, phosphate-buffered solution; SGF, simulated gastric fluid; SIF, simulated intestinal fluid; SEM, standard error of the mean.