Table 1. Genotypic frequencies of the nNOS exon 1c promoter -84 G/A SNP in IHPS and controls.
Genotype | Controls (n = 81) | IHPS (n = 16) | Odds ratio (95% confidence interval) | P value |
---|---|---|---|---|
G/G | 67 (82.72%) | 6 (37.5%) | — | — |
G/A | 13 (16.05%) | 8 (50%) | 6.9 (G/A vs. G/G) (2.0-23.1) | 0.002 |
A/A | 1 (1.23%) | 2 (12.5%) | 22.3 (A/A vs. G/G) (1.8-283.6) | 0.0271 |
A carriers | 14 (17.28%) | 10 (62.5%) | 8.0 (A carriers vs. G/G) (2.5-25.6) | 0.0004 |
The statistical significance of differences between control subjects and patients was tested by Fisher's exact test.