Multiple alleles of HERV-K11q22 and its solo LTRs. The 5′ and 3′ LTRs of the full-length element and the solo LTR contain six polymorphic sites in the 968 base pairs sequenced in the five heterozygous individuals studied. The base pair positions and the identities of these sites are indicated. The ancestral states were determined from character state reconstructions (304, 824, and 928) or assigned by homology to other, closely related HERV-K loci (32, 345, and 575), in cases of ambiguity. There are two alleles (A and B) of the full-length element and three alleles (1, 2, and 3) of the solo LTR. The polymorphic sites that differ from the inferred ancestral sequence are shown in boxes. Of the five heterozygous individuals, two had full-length element A and solo-LTR 2. The remaining individuals each had one of the following combinations: A and solo-LTR 1, B and solo-LTR 1, and B and solo-LTR 3.