Table 1. Polymorphic HERV-K loci in the human genome.
HERV-K | No. of differences between LTRs | Integration time (mya)* |
---|---|---|
11q22 | 4 | 0.81-2.3 |
12q14 | 4 | 0.81-2.3 |
109 | 3 | 0.61-1.8 |
1p31† | 3 | 0.82-2.4‡ |
115 | 5 | 1.0-2.9§ |
108 | 6 | 1.2-3.5 |
mya, million years ago.
Calculations based on the average nucleotide substitution rate of HERV-K loci of 3.77 × 10-9 ± 1.33
This element was not located in the blot but was found by PCR analysis to be polymorphic
Estimated from an alignment of 715 bp, instead of the full-length 968, because of missing sequence data in the 5′ LTR
Integration time estimate taken from ref. 12