Table 1.
The characteristics of 568 CHD patients who were stratified according to serum TSH concentration
|
Serum TSH concentration (mIU/L) |
P value | Total | ||||||
|---|---|---|---|---|---|---|---|---|
| <0.27 | 0.27-1.57 | 1.58-2.88 | 2.89-4.19 | ≥4.2 | ||||
| Age (y) |
64.84(11.64) |
65.47(11.27) |
61.92(11.54) |
63.69(10.57) |
64.46(10.82) |
0.052 |
63.76(11.28) |
|
| SBP (mm Hg) |
137.47(17.01) |
134.77(22.72) |
132.87(19.45) |
136.51(21.17) |
136.94(20.35) |
0.481 |
134.74(20.79) |
|
| DBP (mm Hg) |
80.42(7.77) |
79.02(12.54) |
79.22(11.96) |
78.51(11.83) |
80.43(10.54) |
0.847 |
79.27(11.78) |
|
| FPG (mmol/L) |
6.1328(1.24) |
5.4976(1.04) |
5.3802(1.30) |
5.0863(0.55) |
5.2059(0.83) |
0.001 |
5.3733(1.093) |
|
| TC (mmol/L) |
4.6163 (1.3305) |
4.8699(1.03) |
4.9598(1.15) |
4.9685(1.03) |
5.3518(1.34) |
0.013 |
4.9829(1.15) |
|
| TG (mmol/L) |
1.3226(0.69) |
1.3669(0.82) |
1.7644(1.62) |
1.6951(0.85) |
1.9766(1.66) |
0.003 |
1.6538(1.32) |
|
| LDL (mmol/L) |
3.00(0.851) |
2.91(0.77) |
2.88(0.841) |
2.91 (0.74) |
3.16 (0.91) |
0.111 |
2.94(0.82) |
|
| HDL (mmol/L) |
1.1506(0.29) |
1.2891(0.35) |
1.3229(0.37) |
1.2762(0.32) |
1.3557(0.29) |
0.141 |
1.3060(0.34) |
|
| UA (μmol/L) |
297.9688 (107.94) |
313.9742(90.85) |
321.0955(101.73) |
311.7162(70.90) |
321.63(109.47) |
0.817 |
317.0161(95.98) |
|
| TSH (mIU/L) |
0.1498(0.11) |
1.0532(0.34) |
2.1371(0.35) |
3.5424(0.56) |
19.760(33.33) |
0.000 |
4.6504(14.52) |
|
| FT3 (pmol/L) |
8.1885(6.20) |
4.5007(0.79) |
4.5055(0.71) |
4.5020(0.83) |
3.5891(1.24) |
0.000 |
4.4864(1.58) |
|
| FT4 (pmol/L) |
31.2682(17.85) |
17.5750(2.50) |
17.3971(2.84) |
16.7438(2.44) |
13.4475(4.76) |
0.000 |
17.2147(5.30) |
|
| Smoking status |
A |
17 |
121 |
159 |
72 |
80 |
0.0000 |
|
| B |
0 |
23 |
26 |
3 |
5 |
0.0008 |
|
|
| C |
2 |
23 |
21 |
6 |
1 |
0.0009 |
|
|
| D | 0 | 2 | 5 | 1 | 1 | 0.2222 | ||
1. The data are presented as the mean ± standard deviation (SD). The SD is shown in parentheses.
2. The groups were compared using a Chi-squared test. P-values less than 0.05 were considered statistically significant. 3. Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, free plasma glucose; TC, total cholesterol; TG, triglycerides; LDL, low-density lipoprotein cholesterol; HDL, high-density lipoprotein cholesterol; and UA, uric acid. 4. The following reference ranges were based on our laboratory standards: Plasma glucose (3.9-6.1 mmol/L), total cholesterol (3.6-6.2 mmol/L), triglycerides (<1.71 mmol/L), low-density lipoprotein cholesterol (0–3.36 mmol/L), high-density lipoprotein cholesterol (>1.15 mmol/L), TSH (0.27–4.2 mIU/L), FT3 (3.1-6.8 pmol/L), FT4 (12–22 pmol/L) and uric acid (142–339 μmol/L). 4. The smoking status categories are as follows: A, B, C and D represent no smoking, smoking 1–339, 440–1099, and above 1100 cigarettes per year, respectively. The data are presented as the number of people in each category.