Table 3.
The immunohistochemical features and EBV status of 28 patients with CD20-neagtive diffuse large B-cell lymphoma
| Patient NO. | Age, y/Sex | Sampling Site | CD45 | CD20 | CD79a | CD5 | CD3 | BCL-2 | CD10 | BCL-6 | Mum-1 | Ki-67 (%) | EBER ISH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
68/M |
LN |
+ |
- |
+ |
- |
- |
- |
- |
NT |
+ |
90 |
- |
| 2 |
33/F |
Cevical |
+ |
- |
NT |
NT |
NT |
NT |
NT |
NT |
NT |
NT |
NT |
| 3 |
49/F |
Maxillary Sinus |
+ |
-† |
+ |
NT |
- |
NT |
NT |
NT |
NT |
NT |
NT |
| 4 |
11/M |
Spinal canal |
+ |
- |
+ |
- |
- |
+ |
- |
- |
+ |
80 |
- |
| 5 |
37/M |
Retroperitoneal |
+ |
- |
+ |
- |
- |
- |
NT |
NT |
NT |
80 |
- |
| 6 |
56/M |
Retroperitoneal |
+ |
- |
+ |
- |
- |
+ |
- |
- |
NT |
90 |
- |
| 7 |
54/F |
Stomach |
+ |
- |
+ |
- |
- |
- |
- |
- |
+ |
80 |
- |
| 8 |
73/M |
LN |
+ |
- |
+ |
- |
- |
- |
- |
- |
+ |
80 |
+ |
| 9 |
44/M |
LN |
+ |
- |
+ |
- |
- |
NT |
- |
- |
+ |
90 |
NT |
| 10 |
41/M |
Stomach |
+ |
- |
+ |
NT |
- |
NT |
NT |
NT |
NT |
NT |
NT |
| 11 |
66/M |
Stomach |
+ |
- |
+ |
- |
- |
NT |
- |
- |
- |
80 |
- |
| 12 |
22/M |
Hip |
+ |
- |
+ |
NT |
- |
NT |
NT |
NT |
- |
NT |
NT |
| 13 |
55/M |
LN |
NT |
- |
- |
- |
- |
NT |
- |
NT |
+ |
70 |
- |
| 14 |
19/F |
Stomach |
+ |
- |
+ |
- |
- |
+ |
- |
NT |
+ |
90 |
- |
| 15 |
67/M |
LN |
+ |
- ‡ |
+ |
- |
- |
- |
- |
- |
+ |
70 |
- |
| 16 |
47/F |
Liver |
+ |
- |
+ |
- |
- |
+ |
- |
- |
+ |
90 |
- |
| 17 |
27/M |
Pleural |
+ |
- |
+ |
- |
NT |
+ |
- |
- |
+ |
60 |
- |
| 18 |
83/M |
LN |
+ |
- |
+ |
- |
- |
+ |
+ |
+ |
+ |
100 |
NT |
| 19 |
53/M |
Stomach |
+ |
-§ |
+ |
- |
- |
+ |
+ |
NT |
+ |
100 |
- |
| 20 |
67/M |
LN |
+ |
-¶ |
+ |
- |
- |
+ |
- |
+ |
+ |
90 |
- |
| 21 |
71/M |
Sternum |
+ |
- |
+ |
- |
- |
NT |
+ |
NT |
NT |
90 |
- |
| 22 |
62/F |
LN |
+ |
- |
+ |
- |
- |
+ |
+ |
NT |
+ |
80 |
- |
| 23 |
64/M |
Maxillary sinus |
+ |
- |
NT |
NT |
- |
+ |
- |
- |
+ |
80 |
NT |
| 24 |
35/M |
Lung |
+ |
- |
- |
- |
- |
- |
+ |
NT |
- |
60 |
- |
| 25 |
40/F |
Cevical |
- |
- |
- |
- |
- |
+ |
- |
- |
- |
30 |
- |
| 26 |
18/M |
LN |
+ |
- |
+ |
- |
- |
+ |
NT |
NT |
NT |
30 |
- |
| 27 |
24/F |
Ovarian |
+ |
- |
+ |
- |
- |
- |
- |
- |
- |
70 |
- |
| 28 | 27/M | Mediastinum | + | - | + | - | - | + | - | - | + | 100 | - |
Note: LN, lymphoma node; -, negative; +, positive; NT, not tested; †, ‡, §, ¶: CD20 immunostaining in patient 3, 15, 19 and 20 were performed 2, 3, 4 and 2 times, respectively. All the results of CD20 immunostaining were negative.