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. 2012 Aug 13;7(8):e43205. doi: 10.1371/journal.pone.0043205

Table 2. Bone volume, assessed by micro-CT of tibiae, from 12 week old mice.

Males Females
WT (+/+) (n = 4) Tcal/Tcal (n = 5) WT (+/+) (n = 4) Tcal/Tcal (n = 5)
BV/TV (%) 10.3±1.3 17.7±3.0 14.4±2.4 18.8±1.1
Tb. Th (mmx10−2) 4.2±0.05 4.0±0.1 5.1±0.2 5.4±0.2
Tb. N (mm−1) 2.4±0.3 4.4±0.7* 3.3±0.7 1.9±0.3
SMI 1.6±0.2 0.7±0.1** 1.5±0.3 1.1±0.3
C. BV (mm3) 0.98±0.03 1.16±0.04** 0.89±0.08 1.16±0.04*

WT (+/+), refers to wild-type littermates; BV/TV  =  trabecular bone volume (BV) fraction as a proportion of total volume (TV) of organ; Tb. Th  =  trabecular thickness, Tb. N  =  trabecular number; SMI  =  structural model index; and C.BV  =  cortical bone volume. Values represent means ± SEM; Unpaired student’s t-test: *p<0.05, **p<0.01.