Table 2. Analysis of ClassII HLA and its association with rheumatoid arthritis*.
Generic HLA Class II | RA patients | Controls | p | OR | 95% Confidence Interval |
(n = 132) | (n = 218) | ||||
DRB1 * 01 | 29 | 31 | 0.1019 | 1.61 | 0.95–2.74 |
DRB1 * 0301 | 13 | 25 | 0.7748 | 0.8515 | 0.43–1.70 |
DRB1 * 0302 | 2 | 6 | 0.7044 | 0.5471 | 0.11–2.73 |
DRB1 * 04 | 64 | 63 | 0.0016 | 1.8946 | 1.23–2.79 |
DRB1 * 07 | 17 | 44 | 0.1279 | 0.6132 | 0.34–1.10 |
DRB1 * 08 | 21 | 51 | 0.1466 | 0.6524 | 0.38–1.11 |
DRB1 * 09 | 6 | 12 | 0.8869 | 0.8217 | 0.30–2.21 |
DRB1 * 10 | 9 | 4 | 0.0377 | 3.8118 | 1.16–12.50 |
DRB1 * 11 | 14 | 40 | 0.0865 | 0.5544 | 0.30–1.03 |
DRB1 * 12 | 1 | 2 | 0.6599 | 0.8251 | – |
DRB1 * 13 | 25 | 44 | 0.8912 | 0.9319 | 0.56–1.56 |
DRB1 * 14 | 20 | 30 | 0.8457 | 1.1093 | 0.61–2.00 |
DRB1 * 15 | 20 | 30 | 0.8457 | 2.1093 | 0.61–2.00 |
DRB1 * 16 | 9 | 34 | 0.0291 | 0.4173 | 0.20–0.88 |
DRB3 * | 66 | 128 | 0.2455 | 0.8021 | 0.57–1.13 |
DRB4 * | 81 | 111 | 0.1574 | 1.2960 | 0.92–1.81 |
DRB5 * | 25 | 61 | 0.0995 | 0.6430 | 0.40–1.05 |
DQB1 * 02 | 28 | 57 | 0.3957 | 0.7889 | 0.49–1.28 |
DQB1 * 0301 | 58 | 99 | 0.8942 | 0.9584 | 0.66–1.38 |
DQB1 * 0302 | 56 | 54 | 0.0027 | 1.9046 | 1.30–2.90 |
DQB1 * 0303 | 3 | 19 | 0.0320 | 0.2523 | 0.07–0.90 |
DQB1 * 04 | 19 | 47 | 0.1502 | 0.6419 | 0.37–1.12 |
DQB1 * 05 | 44 | 49 | 0.0529 | 1.5796 | 1.02–2.45 |
DQB1 * 06 | 32 | 72 | 0.1405 | 0.6973 | 0.44–1.10 |
χ2test, significance level p<0.05.