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. 2012 Aug 13;7(8):e42320. doi: 10.1371/journal.pone.0042320

Table 1. Description of key features of the five models.

Model A Model B Model C Model D Model E
Risk of infection and severity of RVGE depend on age Risk of infection and severity depend on the number of previous infections Risk of infection and severity depends on age and the number of previous infections; short delay between infection and onset of infectiousness Risk of infection and severity depends on the number of previous infections Following infection, individuals develop full immunity or become susceptible again
Temporary immunity following infection Temporary immunity following infection Temporary immunity following infection No period of full immunity following infection Probability of developing full immunity depends on the number of previous infections
Severe and mild RVGE are tracked separately and vary in infectiousness; asymptomatic infections do not transmit After 2 infections, subsequent infections are less infectious and not reported After 2 infections, subsequent infections are less infectious and not reported After 4 infections, all individuals develop full immunity (that may wane) After 4 infections, all individuals develop full immunity (that may wane); asymptomatic infections do not transmit
Only severe RVGE cases are reported Only severe RVGE cases are reported Only severe RVGE cases are reported Mild and severe RVGE cases are reported; reporting rate depends on age (<5 or ≥5 years old) Mild and severe RVGE cases are reported