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. 2012 Aug 13;7(8):e42713. doi: 10.1371/journal.pone.0042713

Figure 4. Effect of maternal exposure to constant light and maternal melatonin replacement on the daily rhythm of corticosterone content in the rat fetal adrenal gland at day 18 of gestation.

Figure 4

Mean ± SEM of fetal corticosterone content. Fetal adrenal glands were collected every 4 hours from fetuses obtained from pregnant dams under LD (green symbols), LL (Red symbols) and LL+Mel (Blue symbols). *: Different from other time points for LD (P<0.05; ANOVA and Newman-Keuls). &: Different from other time points for LL+Mel (P<0.05; ANOVA and Newman-Keuls). LL samples are different from LL+Mel and LD samples (P<0.05; Two way ANOVA and Bonferroni). The grey bars indicate the clock time of lights off and of melatonin replacement or placebo during subjective night.