Table 1.
AmB+Fluc400 | AmB+Fluc800 | p-valuea | |
---|---|---|---|
CCSF 14 (mg/L) | |||
n | 9 | 33 | 0.349 |
Geometric Mean | 25.1 | 32.7 | |
80% Confidence Interval | 18.2, 34.7 | 27.7, 38.7 | |
CSerum 14 (mg/L) | |||
n | 7 | 37 | 0.190 |
Geometric Mean | 24.7 | 37.04 | |
80% Confidence Interval | 17.1, 35.5 | 31.6, 43.4 | |
CSerum 70 (mg/L) | |||
n | 4 | 21 | 0.533 |
Geometric Mean | 24.5 | 32.9 | |
80% Confidence Interval | 13.9, 43.1 | 25.8, 42.1 | |
AUCSerum (mg/L) | |||
n | 11 | 38 | <0.001 |
Geometric Mean | 15.4 | 33.8 | |
80% Confidence Interval | 12.4, 19.1 | 30.1, 37.9 |
Based on ANOVA with outcome of the natural log-transformed pharmacokinetic measure.