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. 2004 Jan 26;101(6):1720–1724. doi: 10.1073/pnas.0307915100

Fig. 1.

Fig. 1.

One-year-old ERα-/- mice develop autoimmune glomerulonephritis. Kidney sections from 1-year-old ERα-/- (B) and ERαβ-/- (D) mice stained with hematoxylin/eosin show glomerulonephritis, but WT (A) and ERβ-/- (C) mice do not. Deposition of IgG was detected by immunofluorescence with kidney sections from WT (E and F) and ERα-/- (G and H) mice. IgG deposition in the kidney is shown in ERα-/- (G) but not WT (E) mice. Counterstained nuclei with DAPI are shown in F and H. Fifteen ERα-/- and 15 WT animals were evaluated.