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. Author manuscript; available in PMC: 2013 Sep 15.

Published in final edited form as: Biochem Pharmacol. 2012 Jul 1;84(6):838–850. doi: 10.1016/j.bcp.2012.06.018

Fig. 7 — MG132 effect on 3-methylcholanthrene-induced AhR degradation in p23-specific knockdown stable Hepa1c1c7, Hep3B, and HeLa cells. SA210 was used to detect AhR. Wild type (WT), negative control knockdown stable (NC), and p23-specific knockdown stable p23kd5 Hepa1c1c7 (A), p23kd6 Hep3B (B, top) p23kd8 HeLa (B, bottom) were used. Cells were treated for 6 h with either DMSO, 1 μM 3-methylcholanthrene (3MC), 10 μM MG132, or both. Each lane contained 20 μg of whole cell extract. GAPDH was used for normalization. Western in A was repeated twice and plotted (mean ± SD, n = 3).

Fig. 7 — MG132 effect on 3-methylcholanthrene-induced AhR degradation in p23-specific knockdown stable Hepa1c1c7, Hep3B, and HeLa cells. SA210 was used to detect AhR. Wild type (WT), negative control knockdown stable (NC), and p23-specific knockdown stable p23kd5 Hepa1c1c7 (A), p23kd6 Hep3B (B, top) p23kd8 HeLa (B, bottom) were used. Cells were treated for 6 h with either DMSO, 1 μM 3-methylcholanthrene (3MC), 10 μM MG132, or both. Each lane contained 20 μg of whole cell extract. GAPDH was used for normalization. Western in A was repeated twice and plotted (mean ± SD, n = 3).