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Time spent (s) in the drug-paired chamber on the postconditioning test day following hydrocodone or morphine pairing in the CPP paradigm. Rats conditioned with the highest dose of hydrocodone (5mg/kg) or morphine (5mg/kg) spent more time on the drug side as compared to rats conditioned with saline. *Denotes a significant difference in time spent on the drug-paired side between drug treated versus saline treated rats, n=7 rats per group.
