Table 1. Yeast strains used in this study.
Species | Strain | Source of cloned gene |
Genotype/phenotype | Reference/source |
---|---|---|---|---|
Saccharomyces
cerevisiae |
AD12345678u− (AD1-8u−) |
Matαpdr1-3 ura3 his1 yor1Δ::hisG
snq2Δ::hisGpdr10Δ::hisG pdruΔ:: hisGycf1Δ::hisG pdr3Δ::hisG pdr15 Δ::hisG pdr5Δ::hisG |
Lamping et al., 2007) | |
AD/pABC3 | plasmid vector | AD1-8u−, pdr5Δ::URA3 | Lamping et al., 2007) | |
AD/CaMDR1 | CaATCC10261 | AD1-8u−, pdr5Δ::MDR1-URA3 | (Lamping et al., 2007) | |
AD/CaCDR1A a (7D) |
CaATCC10261 | AD1-8u−, pdr5Δ::CDR1A-URA3 | Lamping et al., 2007) | |
AD/CaCDR1Ba (6C) |
CaATCC10261 | AD1-8u−, pdr5Δ::CDR1B-URA3 | Lamping et al., 2007) | |
AD1002 | CaATCC10261 | AD1-8u−, pdr5Δ::CDR1A-URA3 | Lamping et al., 2007) | |
AD/CaCDR2Ba | CaATCC10261 | AD1-8u−, pdr5Δ::CDR2B-URA3 | Lamping et al., 2007) | |
AD/ERG11 | CaATCC10261 | AD1-8u−, pdr5Δ::ERG11-URA3 | Lamping et al., 2007) | |
AD/CgCDR1 | CgCBS138 | AD1-8u−, pdr5Δ::CgCDR1-URA3 | Lamping et al., 2007) | |
AD/CgCDR2 | CgCBS138 | AD1-8u−, pdr5Δ::CgPDH1-URA3 | Lamping et al., 2007) | |
AD/CnMDR1 | CnCDC551 | AD1-8u−, pdr5Δ:: CnMDR1-URA3 | Lamping et al., 2007) | |
AD/CkABC1 | CkB2399 | AD1-8u−, pdr5Δ:: CkABC1-URA3 | Lamping et al., 2007) | |
AD124567 |
Matαpdr1-3 ura3 his1 yor1Δ::hisG
snq2Δ::hisG pdr10 Δ::hisG pdru Δ::hisG ycf1 Δ::hisG pdr3Δ::hisG |
(Decottignies et al., 1998) | ||
Candida
albicans |
ATCC 10261 | American Type Culture Collection | ||
CIA4 | Δ ura3::imm434/Δura3::imm434 | (Fonzi and Irwin, 1993) | ||
MML33 |
Δ
ura3::imm434/
Δ
ura3::imm434,
Δ cdr1::hisG/ Δ cdr1::hisG |
Nippon Roche (Kanagawa, Japan) |
||
TIMM3163 | Azole-resistant | (Maebashi et al., 2001) Teikyo University (Tokyo, Japan) |
||
TIMM3165 | Azole-resistant | (Maebashi et al., 2001) Teikyo University (Tokyo, Japan) |
||
B59630 | Azole-resistant | (Albertson et al., 1996) F. Odds (Aberdeen, UK) |
||
IFO1060 | Azole-susceptible | Institute for Fermentation (Osaka, Japan) |
||
KB | Azole-resistant | (Albertson et al., 1996) Pfizer (Sandwich, UK) |
||
MML610 | Azole-susceptible TL1 | (Holmes et al., 2008) T. White (Seattle, WA) |
||
MML611 | Azole-resistant TL3 | (Holmes et al., 2008) T. White (Seattle, WA) |
||
C. glabrata | CBS138 | Centraalbureau voor Schimmelcultures (Utrecht, The Netherlands) |
||
C. krusei | B2399 | Centre for Disease Control (Atlanta, GA) |
Separate alleles of each transporter gene from C. albicans ATCC 10261 are designated A or B (Holmes et al., 2006).