Fig. 4.

Comparison of the main features of the human ERVWE1 locus (h, HERVWE1) with the chimpanzee (c, CERVWE1), gorilla (go, GoERVWE1), orangutan (o, OERVWE1), and gibbon (gi, GiERVWE1) orthologous loci. Sequences of the major donor (DS1) and acceptor (AS1, AS2, and AS3) splice sites and the env initiation codon context are indicated in boxes on the schematic representation of the locus. The length and the percentage of similarity (ape/human) of the full-length provirus, 5′ and 3′ LTRs, and the env ORF are expressed at the nucleic acid level.