Table 1.
STOP-PD Subjects' Demographic and Clinical Characteristics Associated with Study Completion and Non-Completion
| Independent Variable | Completer (n=142) Mean (SD) (Range) | Non-Completer (n=117) Mean (SD) (Range) | t | df | P |
|---|---|---|---|---|---|
| Age (years) | 57.7 (16.9) (19–86) | 58.3 (18.7) (18–93) | 0.29 | 257 | 0.77 |
| Education (years) | 12.6 (3.3) (11–20) | 12.4 (3.6) (10–20) | −0.43 | 254 | 0.67 |
| Duration of current depressive episode (months) | 12.8 (30.1) (1–264) | 10.9 (18.4) (1–120) | −0.59 | 254 | 0.55 |
| SADS delusion severity score | 5.7 (0.9) (3–7) | 5.8 (0.9) (3–7) | 0.63 | 257 | 0.52 |
| MMSE total score | 27.0 (3.1) (13–30) | 26.8 (3.0) (15–30) | −0.64 | 251 | 0.52 |
| CIRS-G total score | 4.5 (3.7) (0–16) | 5.5 (4.3) (0–21) | 1.97 | 255 | 0.04 |
| HAM-D (17-item) total score | 29.4 (5.4) (21–45) | 30.2 (5.0) | 1.10 | 257 | 0.27 |
| BPRS total score | 54.1 (10.1) (34–89) | 55.9 (10.2) (39–81) | 1.41 | 257 | 0.16 |
| Suicide Ideation Scale sum of first 5 items | 2.3 (2.8) (0–10) | 2.6 (3.4) (0–10) | 0.91 | 257 | 0.36 |
| Categorical Variables | N (%) | N (%) | x2 | df | p |
| Gender – Male | 48 (33.8) | 45 (38.5) | 0.60 | 1 | 0.43 |
| Hispanic Ethnicity | 16 (11.3) | 14 (11.9) | 0.03 | 1 | 0.96 |
| Race | 0.26 | 2 | 0.87 | ||
| White | 121(85.2) | 97(82.9) | |||
| Black | 15(10.6) | 14(12) | |||
| Asian | 6(4.2) | 6(5.1) | |||
| Marital Status | 2.08 | 3 | 0.55 | ||
| Married | 38(26.8) | 29(24.8) | |||
| Single | 62(43.7) | 44(37.6) | |||
| Widowed | 23(16.2) | 26(22.2) | |||
| Divorced/Separated | 19(13.4) | 18(15.4) | |||
| Living Arrangements | 0.95 | 1 | 0.32 | ||
| Lives Alone | 28(19.7) | 29(24.8) | |||
| Lives with Others | 114(80.3) | 88(75.2) | |||
| Entry Status | 7.50 | 1 | 0.006 | ||
| Inpatient | 88(62.0) | 91(77.8) | |||
| Other | 54(38.0) | 26(22.2) | |||
| Treatment | 6.58 | 1 | 0.01 | ||
| Olanzapine +Sertraline | 81(57.0) | 48(41.0) | |||
| Olanzapine + Placebo | 61(43.0) | 69(59.0) | |||
| Lifetime Episodes of Major Depression | 1.32 | 1 | 0.24 | ||
| 1 | 47(33.1) | 31(26.5) | |||
| >1 | 95(66.9) | 86(73.5) | |||
| Consent | 6.28 | 1 | 0.01 | ||
| Surrogate | 19(13.4) | 30(25.6) | |||
| Self | 123(86.6) | 87(74.4) |
SADS: Schedule for Affective Disorders and Schizophrenia; MMSE: Mini-Mental State Examination; CIRS-G: Cumulative Illness Rating Scale-Geriatrics; HAM-D: Hamilton Depression Rating Scale; BPRS: Brief Psychiatric Rating Scale