Fig 1. Nuclear 3-synuclein levels are increased by oxidative stress in vitro.
(A) Representative alpha-synuclein western blot of nuclear fractions (Syn nuc) from wildtype (WT) and A53T alpha-synuclein-transfected cells +/− dox induction versus untransfected control; actin was used as a normalization control. (B) Densitometric analyses of nuclear alpha-synuclein levels normalized to actin and reported as fold change (n= 4). Values are expressed as mean ± SD; **p<0.01 & ***p<0.001 versus control.