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. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Free Radic Biol Med. 2012 Jun 15;53(4):993–1003. doi: 10.1016/j.freeradbiomed.2012.05.024

Fig 6. Constitutive PGC1-3 overexpression in vitro protects against 3-synuclein-mediated reductions in complex I activity and losses in cell viability.

Fig 6

(A) Mitochondrial complex I activity reported as % untransfected controls in untreated controls, WT and A53T +/− dox, +/− PGC1 alpha. Values are expressed as mean ± SD**p<0.01 & ***p<0.001 compared to control. (B) Cell viability as analyzed in MTT assay reported as % cell viability versus WT syn in WT and A53T transfected cells in the absence or presence of constitutive PGC1alpha cDNA pre- or co-transfection. (looks like a repeat so I deleted it)***p<0.001 versus uninduced WT and A53T, †p<0.05 versus WT dox, §p<0.001 versus A53T dox.