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. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Free Radic Biol Med. 2012 Jun 7;53(4):758–768. doi: 10.1016/j.freeradbiomed.2012.05.041

Fig. 7.

Fig. 7

Knockdown of KEAP1 in A549 cells augments the expression of PPARγ under basal and As2O3-treated conditions. (A) mRNA expression of PPARγ. Cells were treated with As2O3 for 6 h at indicated concentrations (left panel) or 40 μM of As2O3 for indicated time (right panel). *, p < 0.05 vs SCR with the same treatment. (B) KEAP1-KD cells show reduced mRNA expression of CCND1 in response to As2O3 treatment. Cells were treated as (A). (C) Protein level of PPARγ. Cells were treated with As2O3 for 6 h at indicated concentrations. (D) Quantification of (C). n = 3; *p < 0.05 vs. SCR.