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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Exp Neurol. 2012 Jun 5;237(1):238–245. doi: 10.1016/j.expneurol.2012.05.019

Figure 1.

Figure 1

Administration of 5Z-7-oxozeaenol decreased stroke severity in WT mice. a. ICV administration of 1.6 ug of 5Z-7-oxozeaenol 20 minutes prior to stroke led to a statistically significant reduction in stroke volume in cortex (p = 0.014) and total hemisphere (p = 0.008) but not in striatum (p = 0.066) (n = 6 vehicle, 7 drug). b. IP administration of 5Z-7-oxozeaenol (5 mg/kg) at stroke onset led to a statistically significant reduction in stroke volume in cortex (p = 0.011), striatum (p = 0.044), and total hemisphere (p = 0.010) (n = 7 vehicle, 8 drug). c. IP administration of 5Z-7-oxozeaenol (5 mg/kg) 2 hours after onset of stroke led to a statistically significant reduction in stroke volume in cortex (p = 0.007), striatum (p = 0.001), and total hemisphere (p = 0.001) (n = 7 vehicle, 8 drug). Data presented as mean ± s.e.m. * p < 0.05.