TABLE 4.
Clinical Features and Coronary Angiographic Data of Patients with Peripheral Vascular Disease Referred for Pre-Operative Coronary Angiography as Reported in the Literature
| Reference No. (Year) | No. of Patients | Men/Women | Mean age in years (range) | Smoker | Hypertension | Diabetes | Hyperlipidemia | Peripheral territory | Significant CAD§ |
|---|---|---|---|---|---|---|---|---|---|
| 22 (1972) | 100 | 83 (83%)/17 (17%) | 61 (39–81) | 95 (95%) | 48 (48%) | 14 (14%) | 36 (36%) | AAA (n=28), LE (n=72) | 21/28 (75%); 34/72 (47%) |
| 9 (1987) | 84 | 63 (75%)/21 (25%) | 66 (51–79) | 53 (63%) | 54 (64%) | 30 (36%) | 37 (44%) | AAA | 30/39* (76%) |
| 7 (1987) | 42 | 39 (93%)/3 (7%) | 67 (49–78) | NR | 15 (36%) | 6 (14%) | NR | AAA | 36 (86%) |
| 8 (1992) | 37 | 33 (89%)/4 (11%) | 68 (53–76) | 23 (62%) | 20 (54%) | 14 (38%) | 15 (41%) | AAA (n=16), LE (n=21) | 7/16 (44%); 12/21 (57%) |
| 13 (1984) | 1000 | 685 (69%)/315 (31%) | 64 (29–95) | NR | 548 (55%) | 170 (17%) | NR | AAA (n=263), carotid (n=295), LE (n=381), other (n=61)† | 170/263 (65%); 174/295 (59%); 218/381 (57%); 36/61 (59%) |
| 4 (1995) | 125 | 21 (17%)/104 (83%) | 64 (38–83) | NR | 63 (50%) | 19 (15%) | NR | AAA | 35 (28%) |
| 18 (1997) | 102 | 82 (80%)/20 (20%) | 68 (48–83) | 47 (46%) | 61 (60%) | 10 (10%) | 37 (36%) | AAA | 66 (65%) |
| 10 (1997) | 283 (151*) | 259 (92%)/24 (8%) | 72 (45–92) | NR | 90 (32%) | NR | NR | AAA | 52 (34%) |
| 23 (1998) | 50 | 46 (92%)/4 (8%) | 71 | 41 (82%) | 29 (58%) | 9 (18%) | 21 (42%) | AAA | 23 (46%) |
| 16 (2002) | 133 (84*) | 116 (87%)/17 (13%) | 66 (39–84) | NR | NR | NR | NR | TAA (n=45), AAA (n=88) | 36 (43%) |
| 17 (2002) | 94 | 81 (86%)/13 (14%) | 72 | 55 (94%) | 68 (72%) | 14 (15%) | 31 (34%) | AAA | 43 (46%) |
| 21 (2002) | 159 (145*) | 132 (83%)/27 (17%) | 70 (53–87) | NR | 59 (41%) | 15 (10%) | 18 (12%) | AAA | 43 (30%) |
| 20 (2004) | 100 | 89 (89%)/11 (11%) | 71 (56–87) | 58 (58%) | 65 (65%) | 7 (7%) | 45 (45%) | AAA | 47 (47%) |
| 14 (2005) | 420 | 276 (66%)/144 (34%) | 69 | 54 (13%) | 306 (73%) | 118 (28%) | 282 (67%) | carotid | 258 (61%) |
| 5 (2005) | 200 (78*) | 175 (87%)/25 (13%) | ≥70 years ‡ | 136 (68%) | 153 (77%) | 72 (36%) | 89 (45%) | carotid | 73 (94%) |
| 12 (2008) | 82 | 61 (74%)/21 (26%) | 68 (47–88) | 50 (61%) | 53 (65%) | 56 (68%) | 24 (29%) | LE | 27 (33%) |
| 15 (2008) | 122 | 106 (87%)/16 (13%) | 73 | 58 (48%) | 96 (79%) | 15 (12%) | 47 (39%) | AAA | 68 (56%) |
| 11 (2008) | 1048 (823*) | NR | NR | NR | NR | NR | NR | AAA, LE | 626 (76%) |
| 19 (2009) | 208 (105*) | 75 (71%)/30 (29%) | 74 | NR | 70 (67%) | 39 (37%) | NR | AAA, LE | 65 (62%) |
in reference #21, 145 of the 159 patients underwent coronary angiography; in reference #5, 78 of the 200 patients underwent coronary angiography; in reference #10, 151 of the 283 patients underwent coronary angiography; in reference #16, 84 of the 133 patients underwent coronary angiography; in reference #11, 823 of the 1048 patients did not have a previous CABG; in reference #19, 105 of the 208 patients underwent coronary angiography; in reference #9, data is reported for 82 patients, ≥70% lesion was reported in 76% of group 1 (definite clinical evidence of coronary artery disease, n=35) and group 2 (possible clinical evidence of coronary artery disease, n=4), no mention was made regarding group 3 (no clinical evidence of coronary artery disease, n=43)
renal or mesenteric artery stenosis, extremity aneurysms, false aneurysms or complications of prior vascular reconstruction
40 patients with coronary artery disease and 65 patients without coronary artery disease were ≥70 years old
significant CAD defined as ≥70% luminal diameter narrowing of a major epicardial artery, or ≥50% narrowing of the left main coronary artery
AAA= abdominal aortic aneurysm
CABG= coronary artery bypass graft surgery
CAD = coronary artery disease
LE = lower extremity
TAA= thoracic aortic aneurysm
NR= not reported