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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Biomaterials. 2012 Jul 15;33(30):7412–7421. doi: 10.1016/j.biomaterials.2012.06.081

Figure 4. Lentivirius activity following loading within PEG hydrogels.

Figure 4

Viral activity release from and remaining within hydrogels was assessed for PEGnp, PEGmp, and pPEGmp hydrogels. For the measurement of viral activity within hydrogels, the hydrogels were solubilized by the treatment of trypsin for 1 h. Virus in cDMEM or trypsin served as controls for the measurement of viral activity released from or remaining within hydrogels, respectively. Viral activity for each hydrogel condition is reported relative to the respective unencapsulated control (either released from hydrogel or remaining within hydrogel), which is the total amount of virus loaded per hydrogel (8 × 105 LP). Significant differences relative to the respective control based on a t-test are denoted by an asterisk (p<0.05).