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. Author manuscript; available in PMC: 2013 Oct 15.
Published in final edited form as: Exp Cell Res. 2012 Jun 13;318(17):2215–2225. doi: 10.1016/j.yexcr.2012.06.006

Figure 3. Migration and invasion capabilities of mtBALB cybrid cells in the presence of Bay11-7082.

Figure 3

Migration transwell assays were performed using uncoated inserts and invasion assay was conducted on inserts coated with matrigel. (a) The bar graph represents the average of cybrid cells migrated through uncoated inserts in the presence of various concentrations of Bay11-7082. (b) The bar graph shows the average of invading mtBALB cells through the matrigel-coated inserts in the presence of 5μM Bay11-7082. Representative microscopic pictures of stained cells that migrated through the pores of uncoated inserts (c) or invaded through the pores of matrigel coated inserts (d) in the presence or absence of Bay11-7082. The cybrid cells were assayed in triplicate transwells for each experiment, and the averages were graphed with the standard error of the mean (SE. The asterisks indicate that mtBALB cybrid cells showed a statistically significant decrease in migration and invasion from the mtB6 in the presence of NFκB inhibitor Bay11-7082. *P value < 0.0005, **P value < 0.001, ***P value < 0.0001.