Fig. 6.

RT-PCR analysis of mRNA expression for COX-2 in the MKN7 cells exposed to Hp cagA and vacA negative strain and coincubated in the presence of NS-398. a, b represent mRNA expression for β-actin and COX-2, respectively. Lane Control means control cells without Hp infection and NS-398 addition. Following lanes represent mRNA expression for β-actin and COX-2 in MKN7 cells infected with Hp and co-incubated for 3, 6 and 24 h with NS-398. Line NS-398 means MKN7 cells incubated with NS-398 only. c Represents the ratio of COX-2 mRNA over β-actin. Results are mean ± SEM of 5 experiments. Asterisks indicate a significant change (p < 0.05) as compared to control