Figure 2.

Quantitative analyses of dendritic spines in CA1 pyramidal neurons from Mecp2 mutant mice and age-matched wildtype littermates. (a) Representative examples of apical dendritic segments of CA1 pyramidal neurons from P7 wildtype and Mecp2^tm1.1Jae mice (top). Scale bar represents 2 μm.(b) Examples of apical dendritic segments of CA1 pyramidal neurons from P15 wildtype and Mecp2^tm1.1Jae mice (top). (c) Examples of apical dendritic segments of CA1 pyramidal neurons from P40 wildtype and Mecp2^tm1.1Jae mice (top). (d) Dendritic spine density (spines per 10 μm of dendrite). All data are expressed as mean ± SEM. *indicates P < 0.05.