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. 2012 Aug 14;3:250. doi: 10.3389/fimmu.2012.00250

Table 4.

Selected clinical trials of microbicides.

Microbicides Status Phase Type of prevention Alternate study ID Component Comment/references
NCT00262106 Complete III Gel, vaginal MDP301, ISRCTN64716212 PRO 2000/5 gel 0.5% and 2% Not efficacious; McCormack et al., 2010
NCT00153777 Terminated III Gel, vaginal CONRAD, C03-090 Cellulose sulfate gel (6%) No protection, possible enhancement; Van Damme et al., 2008
NCT00213083 Unknown III Gel, vaginal Population council #322 Carraguard (PC-515) No protection; Skoler-Karpoff et al., 2008
NCT00441298 Complete II Gel, vaginal CAPRISA 004 Tenofovir 1% gel 39% efficacy; Abdool Karim et al., 2010
NCT00705679 Active II Gel, vaginal and ART oral VOICE, MTN-003 Tenofovir 1% vaginal gel, emtricitabine/tenofovir disoproxil fumarate Vaginal gel arm halted, no efficacy; 1
NCT00740584 Complete I/II Gel, vaginal SPL7013-003, DAIDS ES number 10730 3% SPL7013 gel (VivaGel) Price et al., 2011
NCT00850837 Recruiting I Gel, vaginal AF 020 Acidform lubricant (Amphora)
NCT01283360 Recruiting I Gel, rectal CONRAD, 1009001 Tenofovir 1% gel

More information about the individual trials can be found using the NCT number and the following databases: www.aidsinfo.nih.gov/clinical-trials; www.clinicaltrials.gov; http://www.avac.org.

1. http://www.niaid.nih.gov/news/newsreleases/2011/Pages/VOICEdiscontinued.aspx