Table 1.
Correlation between CDCA3 expression and clinical classification in OSCCs
| |
|
Results of immunostaining |
|
|
|---|---|---|---|---|
|
Clinical classification |
|
No. patients (%) |
|
|
| Total | CDCA3 negative | CDCA3 positive | p value | |
| Age at surgery (years) |
|
|
|
|
| <60 |
23 |
9 (39) |
14 (61) |
|
| ≧60, <70 |
22 |
11 (50) |
11 (50) |
0.852 |
| ≧70 |
50 |
22 (44) |
28 (56) |
|
| Gender |
|
|
|
|
| Male |
58 |
28 (48) |
30 (52) |
0.317 |
| Female |
37 |
14 (38) |
23 (62) |
|
| T-primary tumor |
|
|
|
|
| T1 |
6 |
3 (50) |
3 (50) |
0.020* |
| T2 |
56 |
30 (54) |
26 (46) |
|
| T3 |
15 |
5 (33) |
10 (67) |
|
| T4 |
18 |
4 (22) |
14 (78) |
|
| T1 + T2 |
62 |
33 (53) |
29 (47) |
0.015* |
| T3 + T4 |
33 |
9 (27) |
24 (73) |
|
| N-regional lymph node |
|
|
|
|
| N (−) |
56 |
25 (45) |
31 (55) |
0.919 |
| N (+) |
39 |
17 (44) |
22 (56) |
|
| Stage |
|
|
|
|
| I |
6 |
3 (50) |
3 (50) |
0.235 |
| II |
36 |
18 (50) |
18 (50) |
|
| III |
17 |
8 (47) |
9 (53) |
|
| IV |
36 |
13 (36) |
23 (64) |
|
| Histopathologic type |
|
|
|
|
| Well |
60 |
26 (43) |
34 (57) |
0.803 |
| Moderately |
31 |
14 (45) |
17 (55) |
|
| Poorly |
4 |
2 (50) |
2 (50) |
|
| Tumor site |
|
|
|
|
| Gingiva |
28 |
9 (32) |
19 (68) |
0.456 |
| Tongue |
51 |
25 (49) |
26 (51) |
|
| Buccal mucosa |
9 |
4 (44) |
5 (56) |
|
| Oral floor | 7 | 4 (57) | 3 (43) | |
*p < 0.05.