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. Author manuscript; available in PMC: 2012 Aug 14.
Published in final edited form as: Free Radic Biol Med. 2010 Jul 16;49(8):1255–1262. doi: 10.1016/j.freeradbiomed.2010.07.006

Figure 1. Sensitivity of Sod2−/− cells to oxidative stress and endogenous ROS generation.

Figure 1

(A) ROS measurement with DHE using whole cell as described in the Materials and Methods section; (B) Lipid oxidation measured as the isoprostane contents. (C) Sensitivity of Sod2−/− cells to inhibitors of mitochondrial respiratory chain. Cell viability was measured using the MTT assay as described in the Materials and Methods section. *p < 0.05 and ** p < 0.01 between wild-type (WT) and Sod2−/− (KO) groups (n=3 experiments).