. 2012 Jul 5;2012:657026. doi: 10.1155/2012/657026

Table 2.

Effect of Thymus vulgaris essential oil (TEO) treatment on exudate volume and leukocytes number 4 hours after carrageenan injection (200 μg/pleural cavity) in rats.

Group	Exudate volume (mL)	Inhibition (%)		(cells/mm³) × 10³
Group	Exudate volume (mL)	Inhibition (%)	Total leukocytes	MN	PMN
Normal	0.16 ± 0.01		6700 ± 450	1800 ± 160	4900 ± 390
Control	0.76 ± 0.03^b		55650 ± 1860^b	8831 ± 644^b	46819 ± 1399^b
Indomethacin (5 mg/kg)	0.33 ± 0.02^a,b	56.7	60250 ± 7600^b	10162 ± 1137^b	50088 ± 6989^b
Celecoxib (10 mg/kg)	0.43 ± 0.03^a,b	43.3	42350 ± 3536^b	6972 ± 1047^b	35378 ± 3774^b
TEO
250 mg/kg	0.62 ± 0.02^a,b	18.4	52696 ± 2558^b	10786 ± 1156^b	41910 ± 2646^b
500 mg/kg	0.61 ± 0.03^a,b	19.7	54729 ± 3090^b	7457 ± 924.9^b	47272 ± 2354^b
750 mg/kg	0.53 ± 0.04^a,b	30.2	41417 ± 2125^a,b	5873 ± 415.7^b	35543 ± 1801^a,b

Data are mean ± SEM of 8–10 animals/group. Indomethacin and celecoxib administered orally were used as reference anti-inflammatory drugs (positive controls). Normal: animals that received injection of saline in the cavity (normal group), Control: animals that received injection of carrageenan in the cavity (negative control). MN: mononuclears cells. PMN: polimorphonuclears cells. ^a P < 0.05 compared to control group; ^b P < 0.05 compared to normal group (ANOVA, Tukey's test).