. 2012 Jul 5;2012:657026. doi: 10.1155/2012/657026

Table 4.

Effect of thymol treatment on exudate volume and leukocytes number 4 hours after carrageenan injection (200 μg/pleural cavity) in rats.

Group	Exsudate volume (mL)	Inhibition (%)		(cells/mm³) × 10³
Group	Exsudate volume (mL)	Inhibition (%)	Total leukocytes	MN	PMN
Normal	0.16 ± 0.01		6700 ± 450	1800 ± 160	4900 ± 390
Control	0.76 ± 0.03		55650 ± 1860^b	8831 ± 644^b	46819 ± 1399^b
Indomethacin (5 mg/kg)	0.33 ± 0.02^a	56.7	60250 ± 7600^b	10162 ± 1137^b	50088 ± 6989^b
Celecoxib (10 mg/kg)	0.43 ± 0.03^a	43.3	42350 ± 3536^b	6972 ± 1047^b	35378 ± 3774^b
Thymol
100 mg/kg	0.73 ± 0.06	—	42306 ± 2429^b	5563 ± 403.6^b	36742 ± 2216^b
200 mg/kg	0.65 ± 0.03	—	46900 ± 2931^b	6609 ± 683.8^b	40290 ± 2357^b
400 mg/kg	0.54 ± 0.05^a	34.2	47600 ± 2987^b	6286 ± 380.3^b	41313 ± 2979^b

Data are mean ± SEM of 8–10 animals/group. Indomethacin and celecoxib administered orally were used as reference anti-inflammatory drugs (positive controls). Normal: animals that received injection of saline in the cavity (normal group), Control: animals that received injection of carrageenan in the cavity (negative control). MN: mononuclears cells. PMN: polimorphonuclears cells. ^a P < 0.05 compared to control group; ^b P < 0.05 compared to normal group (ANOVA, Tukey's test).