Fig 2.

Top 10 significant KEGG pathways enriched by the differentially regulated genes in the mouse lung in response to WT S. aureus infection at 24 h postinoculation compared to PBS control. The corresponding results for the comparison between Hla⁻ infection and PBS control are also listed. The differentially expressed genes with an FDR of <1% and a minimum of a 3-fold change were included in this analysis. The vertical dashed line indicates the cutoff of significance (P < 0.05). P values were corrected by the Benjamini-Hochberg procedure (3).