Table 2.
Genes upregulated during WT S. aureus infection compared to expression during Hla− infection at 24 ha
Symbol | Gene name | Fold change |
---|---|---|
Ccl20 | Chemokine (C-C motif) ligand 20 | 56 |
Cyp27b1 | Cytochrome P450, family 27, subfamily b, polypeptide 1 | 25 |
Ccl11 | Chemokine (C-C motif) ligand 11 | 23 |
Tmem45b | Transmembrane protein 45b | 23 |
Aldh1a3 | Aldehyde dehydrogenase family 1, subfamily A3 | 22 |
Cldn4 | Claudin 4 | 16 |
Slc13a3 | Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 | 14 |
Has1 | Hyaluronan synthase 1 | 11 |
Ngp | Neutrophilic granule protein | 11 |
Pitpnm2 | Phosphatidylinositol transfer protein, membrane associated 2 | 11 |
Ceacam10 | Carcinoembryonic antigen-related cell adhesion molecule 10 | 10 |
Csf3 | Colony-stimulating factor 3 (granulocyte) | 10 |
Il18rap | Interleukin-18 receptor accessory protein | 9.8 |
Kcnk5 | Potassium channel, subfamily K, member 5 | 9.5 |
Fosl1 | Fos-like antigen 1 | 9.3 |
Mctp2 | Multiple C2 domains, transmembrane 2 | 9.0 |
Nipal1 | NIPA-like domain containing 1 | 8.9 |
Sprr1a | Small proline-rich protein 1A | 8.8 |
Ereg | Epiregulin | 8.5 |
Il6 | Interleukin-6 | 8.4 |
Dbn1 | Drebrin 1 | 7.9 |
Lif | Leukemia inhibitory factor | 7.8 |
Hamp | Hepcidin antimicrobial peptide | 7.7 |
Cxcl1 | Chemokine (C-X-C motif) ligand 1 | 7.5 |
Pcp4 | Purkinje cell protein 4 | 7.2 |
Selp | Selectin, platelet | 7.1 |
Zfp783 | Zinc finger protein 783 | 6.9 |
Ptx3 | Pentraxin-related gene | 6.9 |
Plekha7 | Pleckstrin homology domain containing, family A, member 7 | 6.8 |
Ffar2 | Free fatty acid receptor 2 | 6.8 |
Cd80 | CD80 antigen | 6.7 |
Mbp | Myelin basic protein | 6.7 |
Il23a | Interleukin-23, alpha subunit p19 | 6.7 |
Artn | Artemin | 6.5 |
Cldn1 | Claudin 1 | 6.3 |
FDR < 5%.