Fig 1.

The BBB22 and BBB23 proteins demonstrate a high level of identity. Shown is an amino acid sequence alignment of the BBB22 (NP_047008.1) and BBB23 (NP_047009.2) proteins, according to current annotation. Identical amino acids are shaded. Amino acid sequences were aligned using the Clustal W algorithm in the MegAlign program from the DNASTAR Lasergene suite. The putative sequences of the 12 transmembrane domains were predicted using the TMHMM server, version 2.0 (http://www.cbs.dtu.dk/services/TMHMM/), and are indicated with gray underlines. Divergent sequences in putative periplasmic loops 4 and 6 are indicated with black underlines. An alternative prediction for the start codon of BBB23 is indicated with a black arrow.