Fig. 6.

Interaction networks for some groups of TCR-responsive proteins. Different clusters of interacting proteins were identified using STRING to obtain a high confidence evidence network. Connecting lines show reported interaction based on experimental evidence (blue lines) or databases (pink lines). A, proteins interacting directly with the TCR complex or the main reported pathways; B, Rho-GTPases, C, cytoskeletal regulators; D, regulation of transcription; E, pre-mRNA processing; F, trafficking through nucleus; G, microtubule and centrosome assembly.