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. 2012 Mar 21;11(5):77–89. doi: 10.1074/mcp.M111.015362

Fig. 4.

Fig. 4.

Principal component analysis. A, the proteomes of 10 DLBCL cell lines measured in triplicate segregated into ABC-DLBCL and GCB-DLBCL subtypes after filtering for 100% valid values (3,007 proteins). B, loadings of A reveal proteins that strongly drive the segregation in PCA component 1. C, the same analysis as in A but after filtering for 50% valid values (4,991 proteins) and filling the missing values by data imputation results in even stronger separation. D, loadings of C uncover additional known and unknown markers that segregate the ABC and GCB subtypes.