Skip to main content
. 2011 Nov 3;142(1):76–85. doi: 10.1378/chest.11-1782

Figure 1.

Figure 1.

Mast cells in the ASM bundle express TSLP. A, Representative photomicrographs of a bronchial biopsy specimen from asthmatic subjects (original magnification, ×100) showing negative isotype control (i), TSLP staining in ASM bundles (ii), and epithelium (magnification ×400, iii). Sequential sections of the ASM bundle highlighting the same cells across sections showing mast cell tryptase-positive staining (iv) and TSLP (v). The short arrows illustrate the cells that are both tryptase+ and TSLP+ within the ASM bundle. B, Dot plot showing ASM TSLP expression determined by % red hue. C, TSLP-positive cells per square millimeter of lamina propria in subjects with and without asthma. D, TSLP expression in the epithelium by % red hue. Horizontal bar represents median. ASM = airway smooth muscle; TSLP = thymic stromal lymphopoietin.