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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Heart Lung Transplant. 2012 Jul 11;31(9):1018–1024. doi: 10.1016/j.healun.2012.05.018

Figure 1. Host MHC class II is required for acute xeno-rejection.

Figure 1

C2D mice tolerate rat cardiac grafts indefinitely (>100 days, n=5, p<0.005ν). Long-term surviving C2D hosts of rat cardiac grafts (>100 days) then received the adoptive transfer of 1×107 column-purified B6 CD4+ LNCs on day 100 post heart transplantation (see arrow: ↓). Despite this challenge, these grafts continued to survive indefinitely (> than an additional 100 days).