Table 2. Selected Treatments for Prostate Cancer With 1 Year After Diagnosis*.
Characteristics | Year of Diagnosis | P Value† | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
1999 (n = 2151) | 2000 (n = 2106) | 2001 (n = 2150) | 2002 (n = 2448) | 2003 (n = 2345) | 2004 (n = 2349) | 2005 (n = 2380) | 2006 (n = 2538) | 2007 (n = 2451) | ||
No active therapy, No. (%) | 345 (16.0) | 313 (14.9) | 296 (13.8) | 394 (16.1) | 344 (14.7) | 382 (16.3) | 534 (22.4) | 544 (21.4) | 551 (22.5) | <.001 |
Radiation therapy, No. (%) | 998 (46.4) | 982 (46.6) | 1037 (48.2) | 1185 (48.4) | 1130 (48.2) | 1114 (47.4) | 1112 (46.7) | 1266 (49.9) | 1197 (48.8) | .05 |
Brachytherapy | 380 (17.7) | 388 (18.4) | 428 (19.9) | 491 (20.1) | 464 (19.8) | 467 (19.9) | 438 (18.4) | 471 (18.6) | 425 (17.3) | .43 |
External beam | ||||||||||
2-D | 52 (2.4) | 38 (1.8) | 36 (1.7) | 26 (1.1) | 24 (1.0) | 12 (0.5) | 14 (0.6) | 11 (0.4) | <.001 | |
3-D conformal | 767 (35.7) | 755 (35.8) | 756 (35.2) | 775 (31.7) | 561 (23.9) | 466 (19.8) | 354 (14.9) | 319 (12.6) | 221 (9) | <.001 |
IMRT | 20 (0.9) | 151 (6.2) | 345 (14.7) | 482 (20.5) | 574 (24.1) | 747 (29.4) | 761 (31.0) | <.001 | ||
Surgery, No. (%) | <310 (<13.0) | <310 (<13.0) | <310 (<13.0) | <310 (<13.0) | 298 (12.7) | 304 (12.9) | 339 (14.2) | 343 (13.5) | 386 (15.7) | .16 |
Open | 299 (13.9) | 305 (14.5) | 295 (13.7) | 283 (11.6) | 281 (12.0) | 259 (11.0) | 246 (10.3) | 214 (8.4) | 197 (8.0) | <.001 |
Minimally invasive | 17 (0.7) | 45 (1.9) | 93 (3.9) | 129 (5.1) | 189 (7.7) | <.001 | ||||
ADT, No. (%) | 1187 (55.2) | 1140 (54.1) | 1184 (55.1) | 1345 (54.9) | 1265 (53.9) | 1267 (53.9) | 1030 (43.3) | 1093 (43.1) | 880 (35.9) | <.001 |
ADT monotherapy, No. (%) | 531 (24.7) | 522 (24.8) | 539 (25.1) | 602 (24.6) | 601 (25.6) | 567 (24.1) | 419 (17.6) | 414 (16.3) | 345 (14.1) | <.001 |
Abbreviation: ADT, androgen deprivation therapy; IMRT, intensity-modulated radiation therapy.
Where cells had 10 or fewer observations, data have been suppressed to protect patient confidentiality.
From Cochran-Mantel-Haenszel tests for associations between characteristic and year of diagnosis.