Table 3.
Adjusteda logistic regression analyses of the association between previous endoscopy, advanced adenomas, and sessile serrated polyps by anatomic site: Group Health enrollees 1998–2007.
| Controlsb | Rectal and Distal Advanced adenomas | Proximal Advanced adenomas | Rectal and Distal Sessile serrated polyps | Proximal Sessile serrated polyps | |||||
|---|---|---|---|---|---|---|---|---|---|
| N (%) | N (%) | ORa (95% CI) | N (%) | ORa (95% CI) | N (%) | ORa (95% CI) | N (%) | ORa (95% CI) | |
| No prior endoscopy | 740 (43) | 93 (65) | 1.00 (ref) | 49 (62) | 1.00 (ref) | 28 (52) | 1.00 (ref) | 65 (49) | 1.00 (ref) |
| Any Endoscopyc | 964 (57) | 50 (35) | 0.38 (0.26–0.56) | 30 (38) | 0.31 (0.19–0.52) | 26 (48) | 0.64 (0.35–1.15) | 69 (51) | 0.75 (0.50–1.11) |
| Sigmoidoscopy Onlyd | 464 (27) | 30 (21) | 0.48 (0.31–0.76) | 16 (21) | 0.38 (0.21–0.71) | 12 (22) | 0.67 (0.32–1.38) | 30 (22) | 0.71 (0.44–1.14) |
| Colonoscopy Onlyd | 233 (14) | 12 (8) | 0.36 (0.19–0.69) | 7 (9) | 0.28 (0.12–0.64) | 9 (17) | 0.81 (0.36–1.82) | 18 (14) | 0.76 (0.43–1.36) |
| Sigmoidoscopy and Colonoscopyd | 267 (16) | 8 (6) | 0.21 (0.10–0.45) | 7 (9) | 0.24 (0.10–0.56) | 5 (9) | 0.42 (0.15–1.14) | 21 (15) | 0.80 (0.46–1.39) |
Adjusted for age, sex, race, education, BMI, physical activity, family history of colorectal cancer, alcohol intake, smoking status, NSAIDs use, hormone therapy use, and study phase.
Controls include participants with no colorectal pathology, participants with non-advanced adenomas, and participants with hyperplastic polyps
Prior sigmoidoscopy, colonoscopy, or a history or both exams ≥2 years prior to the index colonoscopy
Previous exam ≥2 years prior to the index colonoscopy
Note: 9 study participants had advanced adenomas in both the distal and proximal portions of the colon and were included in both groups
16 study participants had advanced SSPs in both the distal and proximal portions of the colon and were included in both groups