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. Author manuscript; available in PMC: 2013 Mar 14.
Published in final edited form as: J Am Chem Soc. 2012 Mar 6;134(10):4753–4761. doi: 10.1021/ja210535w

Figure 7. The structure of the heme a3-CuB binuclear center, Y244 and Y129 with respect to the positive and negative sides of the inner mitochondrial membrane.

Figure 7

The red spheres are water molecules that are part of the water cluster near the heme a3 propionates. These three water molecules directly link the propionates of heme a3 to Tyr-129 by an H-bonding network (black dashed lines). The radical migration between Tyr-244 and Tyr-129 may occur through the linked Y244, H240, W236, Y129 network. The H-bond distances (in Å) between water molecules a, b and c and that between c and the oxygen of Y129 are indicated. The figure was made from PDB ID: 3AG3 with PyMol Molecular Graphics Software (Delano Scientific, LLC).