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. Author manuscript; available in PMC: 2012 Aug 14.

Published in final edited form as: J Matern Fetal Neonatal Med. 2008 Sep;21(9):652–659. doi: 10.1080/14767050802215193

Figure 2a and 2b. After adjusting for total protein concentration, the median amniotic fluid concentration of SP-A and of SP-B was significantly higher at term than during the mid-trimester of pregnancy (SP-A/total protein; term no labor: median 3.05 μg/mg, range 1.15–6.87 μg/mg vs. mid-trimester: median 0.36 μg/mg, range 0.09–1.59 μg/mg; p<0.001 and SP-B/total protein, term no labor: median 0.30 μg/mg, range 0.03–2.11 μg/mg vs. mid-trimester: median 0 μg/mg, range 0–0.08 μg/mg; p<0.001). Amniotic fluid SP-A concentration after adjusting for total protein concentration in women at term in labor was lower than those not in labor (term labor: median 1.45 μg/mg, range 0.8–25.18 μg/mg vs. term not in labor: median 3.05 μg/mg, range 1.15–6.87 μg/mg; p<0.001). There was no significant difference in the median amniotic fluid concentration of SP-B/total protein in women with and without labor (term labor: median 0.23 μg/mg, range 0.04–5.58 μg/mg vs. term not in labor: median 0.30 μg/mg, range 0.03–2.11 μg/mg; p=0.2) *One data point in the term labor group was an outlier (SP-B/total protein: 5.58 μg/mg) and is not shown in the figure. *p<0.05.

Figure 2a and 2b. After adjusting for total protein concentration, the median amniotic fluid concentration of SP-A and of SP-B was significantly higher at term than during the mid-trimester of pregnancy (SP-A/total protein; term no labor: median 3.05 μg/mg, range 1.15–6.87 μg/mg vs. mid-trimester: median 0.36 μg/mg, range 0.09–1.59 μg/mg; p<0.001 and SP-B/total protein, term no labor: median 0.30 μg/mg, range 0.03–2.11 μg/mg vs. mid-trimester: median 0 μg/mg, range 0–0.08 μg/mg; p<0.001). Amniotic fluid SP-A concentration after adjusting for total protein concentration in women at term in labor was lower than those not in labor (term labor: median 1.45 μg/mg, range 0.8–25.18 μg/mg vs. term not in labor: median 3.05 μg/mg, range 1.15–6.87 μg/mg; p<0.001). There was no significant difference in the median amniotic fluid concentration of SP-B/total protein in women with and without labor (term labor: median 0.23 μg/mg, range 0.04–5.58 μg/mg vs. term not in labor: median 0.30 μg/mg, range 0.03–2.11 μg/mg; p=0.2) *One data point in the term labor group was an outlier (SP-B/total protein: 5.58 μg/mg) and is not shown in the figure. *p<0.05.