Table 3.

The HAS-BLED score for estimating risk of bleeding^*: Points are allocated by the HAS-BLED criteria (hypertension [SBP > 160 mm Hg], 1 point; abnormal renal^† or liver^‡ function [1 point each], 1 or 2 points; stroke [caused by a bleed], 1 point; bleeding, 1 point; labile INR,^§ 1 point; elderly [age > 65 y], 1 point; drugs [ASA or NSAIDs] or alcohol [≥ 8 drinks/wk] [1 point each], 1 or 2 points).

HAS-BLED SCORE	MAJOR BLEED* RATE, %/Y
0	1.13
1	1.02
2	1.88
3	3.74
4	8.70
5	12.50

ASA—acetylsalicylic acid, INR—international normalized ratio, NSAID—nonsteroidal anti-inflammatory drugs, SBP—systolic blood pressure.

^*A score of ≥ 3 indicates the patient is at high risk of a major bleed. Major bleed is defined as an intracranial bleed, a drop in hemoglobin level of > 20 g/L, need for transfusion, or hospitalization.

^†Abnormal renal function is defined as transplantation, dialysis, or serum creatinine level of > 200 μmol/L.

^‡Abnormal liver function is defined as biochemical evidence of abnormal liver enzymes (aspartate aminotransferase, alanine aminotransferase, or alkaline phosphatase levels that are > 3 times the upper limit of normal, in association with a bilirubin level > 2 times the upper limit of normal), or chronic liver disease (eg, cirrhosis).

^§Labile INR is defined as being in the therapeutic range < 60% of the time.