Table 2.
Typing of MHC class I alleles of SIV-infected animals
| Animal # | A01 | A02 | A08 | A11 | B01 | B03 | B04 | B08 | B17 | MHC scorea |
|---|---|---|---|---|---|---|---|---|---|---|
| 29276 |
- |
- |
- |
- |
- |
- |
- |
- |
- |
0 |
| 32186 |
- |
- |
- |
- |
- |
- |
- |
- |
- |
0 |
| 30577 |
+ |
- |
- |
+ |
- |
- |
- |
- |
- |
+1 |
| 33088 |
- |
- |
- |
- |
+ |
- |
- |
+ |
- |
0 |
| 33091 |
+ |
- |
- |
- |
- |
- |
- |
+ |
- |
+2 |
| CNPRC frequency (%)b |
18.8 | 13.8 | 13.0 | 9.1 | 29.9 | 1.2 | 1.5 | 7.1 | 11.2 |
aThe MHC score was calculated by adding one point for each protective allele (Mamu-A*01, B*08, B*17) and subtracting a point for Mamu-B*01, which has been associated with higher viral levels; other alleles are given a zero score [18-21].
bFrequency of alleles in the general rhesus macaque colony of the California National Primate Research Center; there was no statistically significant difference in frequency between the 5 SIV-infected animals and the general frequency for any of these alleles (p values > 0.5).