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. 2012 Jul 17;9:57. doi: 10.1186/1742-4690-9-57

Table 7.

Pathological observations at time of euthanasia

Animal number Most significant findings
29276
Chronic interstitial nephritis with tubular atrophy
Hypophosphatemic osteomalacia
Mild generalized lymphoid hyperplasia
30577
Lymphofollicular hyperplasia, mild (inguinal, axillary, tracheobronchial, and mesenteric lymph nodes; MALT (mucosa-associated lymphoid tissue) of cecum and stomach) to moderate (tonsil, spleen, ileocecocolic lymph nodes).
32186
Kidney: polycystic chronic interstitial nephritis with tubular atrophy
Lymph nodes: mild paracortical hyperplasia and mild loss of germinal centers
33088
Mild multifocal hepatitis, mild colitis, mild tracheitis
33091
Heart: valvular vegetative endocarditis
 
Bone marrow and ileum: moderate multifocal lymphoid hyperplasia
 
Lymph nodes: mild to moderate paracortical hyperplasia with indistinct germinal centers
  Spleen: mild lymphoid depletion