Table 7.
Pathological observations at time of euthanasia
| Animal number | Most significant findings |
|---|---|
|
29276 |
Chronic interstitial nephritis with tubular atrophy |
| Hypophosphatemic osteomalacia | |
| Mild generalized lymphoid hyperplasia | |
|
30577 |
Lymphofollicular hyperplasia, mild (inguinal, axillary, tracheobronchial, and mesenteric lymph nodes; MALT (mucosa-associated lymphoid tissue) of cecum and stomach) to moderate (tonsil, spleen, ileocecocolic lymph nodes). |
|
32186 |
Kidney: polycystic chronic interstitial nephritis with tubular atrophy |
| Lymph nodes: mild paracortical hyperplasia and mild loss of germinal centers | |
|
33088 |
Mild multifocal hepatitis, mild colitis, mild tracheitis |
|
33091 |
Heart: valvular vegetative endocarditis |
| |
Bone marrow and ileum: moderate multifocal lymphoid hyperplasia |
| |
Lymph nodes: mild to moderate paracortical hyperplasia with indistinct germinal centers |
| Spleen: mild lymphoid depletion |