Figure 4.
Gene expression profiles in young, aged, and Alzheimer’s disease (AD) samples using hippocampal tissue show similar patterns of change with qPCR and microarray analysis. qPCR (A,B) demonstrated significant gene upregulation of CD14, TLR2, TL4, TLR7, MYD88 and downregulation of TOLLIP in aging, confirming microarray results (C,D). **** P < 0.0001, ***P < 0.005, **P < 0.01, *P < 0.05.